Authors: Duk-Hee Lee, In-kyu Lee, Kyungeun Song, Michael Steffes, William Toscano, Beth A. Baker, David R. Jacobs, Jr
Source: Book: Diabetes Care 29
Date: July 2016
Link: http://care.diabetesjournals.org/content/diacare/29/7/1638.full.pdf
Summary: In a study with over 2000 participants, diabetes prevalence was strongly/consistently correlated with six persistent organic pollutant concentrations after adjustments made for age, sex, BMI, etc.
Learned: Because of bioaccumulation, POPs can travel down the food chain from animal to animal as they are consumed
ReplyDeleteQuestion: How does the insulin biologically result in the increased exposure to POPs?
Learned: High amount of exposure to organic pollutants is less harmful than constant exposure over a long period of time. Those who are obese will also increase the toxicity and retention time of these organic pollutants.
ReplyDeleteQuestion: What pollutant is the most harmful? Is there a specific pollutant that causes this, or simply just the mix of pollutants?
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ReplyDeleteToxins from POPs like Dioxin exposure increases the risk of diabetes where there is a beta cell dysfunction. How can we reduce the risk of being exposed to POPs when buying/eating fish?
ReplyDeleteSomething I learned from this is that the bio-accumulation starts from the producers containing organic pollutants and each consumer from the food chain after that will accumulate more organic pollutant which is found to stay with people who have diabetes.
ReplyDeleteQuestion: Does this mean that people with diabetes should stay away from food sources that go through multiple levels of the food chain?
There is a strong correlation between the bioaccumulation of persistent organic pollutants and becoming diabetic.
ReplyDeleteWhat is in dioxin exposure that causes an increase risk of becoming diabetic?
Bio accumulation puts people at a great risk of consuming toxins because it is difficult to determine the contaminants that have entered the food we are eating.
ReplyDeleteWhy do people with diabetes retain these pollutants more easily and what can be done to counter this effect?
What I learned: Small amounts of toxins can become a serious issue as they build up inside the organs of fish through bioaccumulation.
ReplyDeleteQuestion: How much toxicity does it take to become a serious causer of diabeties?
Two questions:
ReplyDelete(1) How did the researchers adjust data for BMI, age, etc?
(2) Could you find GC data (chromatograms, maybe) for POPs?