Title: Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle
Link: http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2013.267336/full
Author: E.A.F. Herbst, S. Paglialunga, C. Gerling, J. Whitfield, K. Mukai, A. Chabowski, G.J.F. Heigenhauser, L.L. Spriet, G.P. Holloway
The research done by these scientists supports the claim that a diet enriched with omega-3 fatty acids will show an increase in omega-3 concentration in the mitochondrial membrane of human muscle tissue. This leads to the assumption that more ATP to be created during oxidative phosphorylation. However, direct evidence suggesting improved mitochondrial oxidative phosphorylation does not exist in human skeletal muscle. But, it has been shown to improve the efficiency of oxygen use in in the hear tissue of rats, which leads to the question of whether humans also have improved mitochondrial respiratory function with omega-3 PUFA supplementation. Said research was not discussed in this article.
In addition, the increased concentration of omega-3 fatty acids in the skeletal muscle tissue displaces the omega-6 fatty acids from some phsopholipid species, which can decrease inflammation.
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